Why Toll-Like Receptors genes are so polymorphic?

Toll-like receptors (TLRs) are pattern recognition receptors (PRRs) considered to be the primary sensors of pathogens in innate immunity. Genetic variants could be associated to differences in breed innate immune response to pathogens and thus to susceptibility to infections or autoimmune diseases....

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Bibliographic Details
Main Author: Armand Sánchez
Format: Article
Language:English
Published: Università degli Studi di Milano 2016-06-01
Series:International Journal of Health, Animal Science and Food Safety
Subjects:
Online Access:http://riviste.unimi.it/index.php/haf/article/view/7232