Transcriptional changes in response to X chromosome dosage in the mouse: implications for X inactivation and the molecular basis of Turner Syndrome
<p>Abstract</p> <p>Background</p> <p>X monosomic mice (39,XO) have a remarkably mild phenotype when compared to women with Turner syndrome (45,XO). The generally accepted hypothesis to explain this discrepancy is that the number of genes on the mouse X chromosome which...
Main Authors: | Sargent Carole A, Bauer Julien, Ojarikre Andrew, Burgoyne Paul S, Lopes Alexandra M, Amorim António, Affara Nabeel A |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-02-01
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Series: | BMC Genomics |
Online Access: | http://www.biomedcentral.com/1471-2164/11/82 |
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