Triggered radiosensitizer delivery using thermosensitive liposomes and hyperthermia improves efficacy of radiotherapy: An in vitro proof of concept study.

INTRODUCTION:To increase the efficacy of chemoradiation and decrease its toxicity in normal tissue, a new concept is proposed, local radiosensitizer delivery, which combines triggered release of a radiosensitizer from thermosensitive liposomes with local hyperthermia and radiotherapy. Here, key aspe...

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Bibliographic Details
Main Authors: Helena C Besse, Clemens Bos, Maurice M J M Zandvliet, Kim van der Wurff-Jacobs, Chrit T W Moonen, Roel Deckers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6143263?pdf=render