Targeting PI3K/Akt/mTOR Signaling In Cancer

The phosphatidylinositol-3-kinase (PI3K)/Akt and the mammalian target of Rapamycin (mTOR) signaling pathways are two pathways crucial to many aspects of cell growth and survival, in physiological as well as in pathological conditions (e.g. cancer). Indeed, they are so interconnected that, in a certa...

Full description

Bibliographic Details
Main Authors: Camillo ePorta, Chiara ePaglino, Alessandra eMosca
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Oncology
Subjects:
Akt
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00064/full