Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL
Cholesterol biosynthesis is among the most intensely regulated processes in biology. Synthetic rates vary over hundreds of fold depending on the availability of an external source of cholesterol. Studies of this feedback regulatory process have a rich history. The field began 75 years ago when Rudol...
Main Authors: | Michael S. Brown, Joseph L. Goldstein |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2009-01-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520305812 |
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