Genetic polymorphism rs6922269 in the MTHFD1L gene is associated with survival and baseline active vitamin B12 levels in post-acute coronary syndromes patients.

Genetic polymorphism rs6922269 in the MTHFD1L gene is associated with survival and baseline active vitamin B12 levels in post-acute coronary syndromes patients.

BACKGROUND AND AIMS: The methylene-tetrahydrofolate dehydrogenase (NADP+ dependent) 1-like (MTHFD1L) gene is involved in mitochondrial tetrahydrofolate metabolism. Polymorphisms in MTHFD1L, including rs6922269, have been implicated in risk for coronary artery disease (CAD). We investigated the assoc...

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Bibliographic Details
Main Authors: Barry R Palmer, Sandy Slow, Katrina L Ellis, Anna P Pilbrow, Lorraine Skelton, Chris M Frampton, Suetonia C Palmer, Richard W Troughton, Tim G Yandle, Rob N Doughty, Gillian A Whalley, Michael Lever, Peter M George, Stephen T Chambers, Chris Ellis, A Mark Richards, Vicky A Cameron
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3949666?pdf=render

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http://europepmc.org/articles/PMC3949666?pdf=render

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