Mitochondrial Ceramide Effects on the Retinal Pigment Epithelium in Diabetes

Mitochondrial Ceramide Effects on the Retinal Pigment Epithelium in Diabetes

Mitochondrial damage in the cells comprising inner (retinal endothelial cells) and outer (retinal pigment epithelium (RPE)) blood–retinal barriers (BRB) is known to precede the initial BRB breakdown and further histopathological abnormalities in diabetic retinopathy (DR). We previously demonstrated...

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Bibliographic Details
Main Authors: Yan Levitsky, Sandra S. Hammer, Kiera P. Fisher, Chao Huang, Travan L. Gentles, David J. Pegouske, Caimin Xi, Todd A. Lydic, Julia V. Busik, Denis A. Proshlyakov
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
diabetes
retinopathy
acid sphingomyelinase
mitochondria
ceramide
sphingolipid
Online Access:https://www.mdpi.com/1422-0067/21/11/3830

Internet

https://www.mdpi.com/1422-0067/21/11/3830

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