In vitro activity of rifampicin and verapamil combination in multidrug-resistant mycobacterium tuberculosis.

The aim of the present study was to evaluate the effect of the combination of rifampicin (RIF) and verapamil (VP) against the Mycobacterium tuberculosis H37Rv reference strain and six multidrug-resistant (MDR) M. tuberculosis clinical isolates by determining Time-Kill Curves and the ability to efflu...

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Main Authors: Fernanda de Oliveira Demitto, Renata Claro Ribeiro do Amaral, Flaviane Granero Maltempe, Vera Lúcia Dias Siqueira, Regiane Bertin de Lima Scodro, Mariana Aparecida Lopes, Katiany R Caleffi-Ferracioli, Pedro Henrique Canezin, Rosilene Fressatti Cardoso
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4331551?pdf=render