Clinical-Scale Cultures of Cord Blood CD34 Cells to Amplify Committed Progenitors and Maintain Stem Cell Activity

We developed a clinical-scale cord blood (CB) cell ex vivo procedure to enable an extensive expansion of committed progenitors—colony-forming cells (CFCs) without impairing very primitive hematopoietic stem cells (HSCs). CD34 ++ cells, selected from previously cryopreserved and thawed CB units, were...

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Bibliographic Details
Main Authors: Zoran Ivanovic, Pascale Duchez, Jean Chevaleyre, Marija Vlaski, Xavier Lafarge, Bernard Dazey, Elodie Robert-Richard, Frédéric Mazurier, Jean-Michel Boiron
Format: Article
Language:English
Published: SAGE Publishing 2011-10-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368910X552853