Stochiometric quantification of the thiol redox proteome of macrophages reveals subcellular compartmentalization and susceptibility to oxidative perturbations

Stochiometric quantification of the thiol redox proteome of macrophages reveals subcellular compartmentalization and susceptibility to oxidative perturbations

Posttranslational modifications of protein cysteine thiols play a significant role in redox regulation and the pathogenesis of human diseases. Herein, we report the characterization of the cellular redox landscape in terms of quantitative, site-specific occupancies of both S-glutathionylation (SSG)...

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Bibliographic Details
Main Authors: Jicheng Duan, Tong Zhang, Matthew J. Gaffrey, Karl K. Weitz, Ronald J. Moore, Xiaolu Li, Ming Xian, Brian D. Thrall, Wei-Jun Qian
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Redox Biology
Subjects:
Protein thiols
Redox modification
Redox proteomics
S-glutathionylation
Site-occupancy
Stoichiometry
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720308545

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http://www.sciencedirect.com/science/article/pii/S2213231720308545

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