Vacuole-targeting fungicidal activity of amphotericin B

Invasive fungal infections are recognized as major threats to patients with immune depression as well as those with cancer chemotherapy. Amphotericin B (AmB), a classical antifungal agent with a polyene macrolide structure, is widely used for the control of serious fungal infections. However, the cl...

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Bibliographic Details
Main Authors: Akira eOgita, Ken-ichi eFujita, Toshio eTanaka
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-03-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2012.00100/full