Cx43-Associated Secretome and Interactome Reveal Synergistic Mechanisms for Glioma Migration and MMP3 Activation

Cx43-Associated Secretome and Interactome Reveal Synergistic Mechanisms for Glioma Migration and MMP3 Activation

Extracellular matrix (ECM) remodeling, degradation and glioma cell motility are critical aspects of glioblastoma multiforme (GBM). Despite being a rich source of potential biomarkers and targets for therapeutic advance, the dynamic changes occurring within the extracellular environment that are spec...

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Bibliographic Details
Main Authors: Qurratulain Aftab, Marc Mesnil, Emmanuel Ojefua, Alisha Poole, Jenna Noordenbos, Pierre-Olivier Strale, Chris Sitko, Caitlin Le, Nikolay Stoynov, Leonard J. Foster, Wun-Chey Sin, Christian C. Naus, Vincent C. Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Neuroscience
Subjects:
secretome
MMP3
osteopontin
ARK1B10
glioma
migration
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00143/full

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https://www.frontiersin.org/article/10.3389/fnins.2019.00143/full

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