Disruption of pdgfra alters endocardial and myocardial fusion during zebrafish cardiac assembly

Disruption of pdgfra alters endocardial and myocardial fusion during zebrafish cardiac assembly

Cardiac development in vertebrates is a finely tuned process regulated by a set of conserved signaling pathways. Perturbations of these processes are often associated with congenital cardiac malformations. Platelet-derived growth factor receptor α (PDGFRα) is a highly conserved tyrosine kinase recep...

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Bibliographic Details
Main Authors: Suzan El-Rass, Shahram Eisa-Beygi, Edbert Khong, Koroboshka Brand-Arzamendi, Antonio Mauro, Haibo Zhang, Karl J. Clark, Stephen C. Ekker, Xiao-Yan Wen
Format: Article
Language:English
Published: The Company of Biologists 2017-03-01
Series:Biology Open
Subjects:
Pdgfra
Gene trapping
Heart development
Cardiac fusion
Zebrafish
Online Access:http://bio.biologists.org/content/6/3/348

Internet

http://bio.biologists.org/content/6/3/348

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