Esmolol indirectly stimulates vagal nerve activity in endotoxemic pigs
Abstract Background There is an increasing interest in beta-blockade as a therapeutic approach to sepsis following consistent experimental findings of attenuation of inflammation and improved survival with beta1 selective antagonist. However, the mechanism of these beneficial effects remains very un...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2018-07-01
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Series: | Intensive Care Medicine Experimental |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s40635-018-0178-1 |