Esmolol indirectly stimulates vagal nerve activity in endotoxemic pigs

Abstract Background There is an increasing interest in beta-blockade as a therapeutic approach to sepsis following consistent experimental findings of attenuation of inflammation and improved survival with beta1 selective antagonist. However, the mechanism of these beneficial effects remains very un...

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Bibliographic Details
Main Authors: Jerome Aboab, Louis Mayaud, Veronique Sebille, Rodrigo de Oliveira, Merce Jourdain, Djillali Annane
Format: Article
Language:English
Published: SpringerOpen 2018-07-01
Series:Intensive Care Medicine Experimental
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40635-018-0178-1