Valved holding chamber drug delivery is dependent on breathing pattern and device design
Small children with airway obstruction breathe with very low tidal volumes (VT) and high respiratory rates (RRs). These extreme respiratory patterns affect drug delivery unpredictably through valved holding chambers (VHCs). We compared in an in vitro study the effectiveness of two VHCs, one small (1...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
European Respiratory Society
2019-02-01
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| Series: | ERJ Open Research |
| Online Access: | http://openres.ersjournals.com/content/5/1/00158-2018.full |