Cardiomyocyte specific deletion of Crif1 causes mitochondrial cardiomyopathy in mice.

Mitochondria are key organelles dedicated to energy production. Crif1, which interacts with the large subunit of the mitochondrial ribosome, is indispensable for the mitochondrial translation and membrane insertion of respiratory subunits. To explore the physiological function of Crif1 in the heart,...

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Bibliographic Details
Main Authors: Juhee Shin, Seok Hong Lee, Min-Chul Kwon, Dong Kwon Yang, Ha-Rim Seo, Jaetaek Kim, Yoon-Young Kim, Sun-Kyoung Im, Evan Dale Abel, Kyong-Tai Kim, Woo Jin Park, Young-Yun Kong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3537664?pdf=render