Expanding the genome-targeting scope and the site selectivity of high-precision base editors
Base editors can be limited by precision and the size of the target window. Here the authors test Cas9s that recognise alternative PAMs to obtain a series of high-precision editors.
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-14465-z |