Sclerosing Sialadenitis Is Associated With Salivary Gland Hypofunction and a Unique Gene Expression Profile in Sjögren’s Syndrome

Sclerosing Sialadenitis Is Associated With Salivary Gland Hypofunction and a Unique Gene Expression Profile in Sjögren’s Syndrome

PurposeTo develop a novel method to quantify the amount of fibrosis in the salivary gland and to investigate the relationship between fibrosis and specific symptoms associated with Sjögren’s syndrome (SS) using this method.Materials and MethodsParaffin-embedded labial salivary gland (LSG) slides fro...

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Bibliographic Details
Main Authors: Hongen Yin, Thomas J. F. Pranzatelli, Benjamin N. French, Nan Zhang, Blake M. Warner, John A. Chiorini, NIDCD/NIDCR Genomics and Computational Biology Core
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
Sjögren’s syndrome
salivary gland interstitial fibrosis
sclerosing sialadenitis
salivary gland hypofunction
transcriptomic gene expression profile
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.699722/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.699722/full

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