MFGE8 does not influence chorio-retinal homeostasis or choroidal neovascularization in vivo.

Milk fat globule-epidermal growth factor-factor VIII (MFGE8) is necessary for diurnal outer segment phagocytosis and promotes VEGF-dependent neovascularization. The prevalence of two single nucleotide polymorphisms (SNP) in MFGE8 was studied in two exsudative or "wet" Age-related Macular D...

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Main Authors: William Raoul, Lucie Poupel, David-Alexandre Tregouet, Sophie Lavalette, Serge Camelo, Nicole Keller, Sophie Krumeich, Bertrand Calippe, Xavier Guillonneau, Francine Behar-Cohen, Salomon-Yves Cohen, Holger Baatz, Christophe Combadière, Clotilde Théry, Florian Sennlaub
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3305292?pdf=render