The association between Alu hypomethylation and severity of type 2 diabetes mellitus

The association between Alu hypomethylation and severity of type 2 diabetes mellitus

Abstract Background Cellular senescence due to genomic instability is believed to be one of the mechanisms causing health problems in diabetes mellitus (DM). Low methylation levels of Alu elements or Alu hypomethylation, an epigenomic event causing genomic instability, were commonly found in aging p...

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Bibliographic Details
Main Authors: Jirapan Thongsroy, Maturada Patchsung, Apiwat Mutirangura
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Clinical Epigenetics
Subjects:
DNA methylation
Diabetes mellitus
Genomic instability
Alu
Senescence
Online Access:http://link.springer.com/article/10.1186/s13148-017-0395-6

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http://link.springer.com/article/10.1186/s13148-017-0395-6

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