A robust culture system to generate neural progenitors with gliogenic competence from clinically relevant induced pluripotent stem cells for treatment of spinal cord injury

A robust culture system to generate neural progenitors with gliogenic competence from clinically relevant induced pluripotent stem cells for treatment of spinal cord injury

Abstract Cell‐based therapy targeting spinal cord injury (SCI) is an attractive approach to promote functional recovery by replacing damaged tissue. We and other groups have reported the effectiveness of transplanting neural stem/progenitor cells (NS/PCs) derived from human induced pluripotent stem...

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Bibliographic Details
Main Authors: Yasuhiro Kamata, Miho Isoda, Tsukasa Sanosaka, Reo Shibata, Shuhei Ito, Toshiki Okubo, Munehisa Shinozaki, Mitsuhiro Inoue, Ikuko Koya, Shinsuke Shibata, Tomoko Shindo, Morio Matsumoto, Masaya Nakamura, Hideyuki Okano, Narihito Nagoshi, Jun Kohyama
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:Stem Cells Translational Medicine
Subjects:
HLA‐homo
induced pluripotent stem cells
neural stem progenitor cells
oligodendrocyte
remyelination
spinal cord injury
Online Access:https://doi.org/10.1002/sctm.20-0269

Internet

https://doi.org/10.1002/sctm.20-0269

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