Functional and molecular characterisation of EO771.LMB tumours, a new C57BL/6-mouse-derived model of spontaneously metastatic mammary cancer

Functional and molecular characterisation of EO771.LMB tumours, a new C57BL/6-mouse-derived model of spontaneously metastatic mammary cancer

The translation of basic research into improved therapies for breast cancer patients requires relevant preclinical models that incorporate spontaneous metastasis. We have completed a functional and molecular characterisation of a new isogenic C57BL/6 mouse model of breast cancer metastasis, comparin...

Full description

Bibliographic Details
Main Authors: Cameron N. Johnstone, Yvonne E. Smith, Yuan Cao, Allan D. Burrows, Ryan S. N. Cross, Xiawei Ling, Richard P. Redvers, Judy P. Doherty, Bedrich L. Eckhardt, Anthony L. Natoli, Christina M. Restall, Erin Lucas, Helen B. Pearson, Siddhartha Deb, Kara L. Britt, Alexandra Rizzitelli, Jason Li, Judith H. Harmey, Normand Pouliot, Robin L. Anderson
Format: Article
Language:English
Published: The Company of Biologists 2015-03-01
Series:Disease Models & Mechanisms
Subjects:
Breast cancer
Syngeneic preclinical models
Metastasis
Tumour subtyping
Estrogen receptor alpha
Online Access:http://dmm.biologists.org/content/8/3/237

Internet

http://dmm.biologists.org/content/8/3/237

Similar Items