Formation and differentiation of multiple mesenchymal lineages during lung development is regulated by beta-catenin signaling.

Formation and differentiation of multiple mesenchymal lineages during lung development is regulated by beta-catenin signaling.

The role of ss-catenin signaling in mesodermal lineage formation and differentiation has been elusive.To define the role of ss-catenin signaling in these processes, we used a Dermo1(Twist2)(Cre/+) line to target a floxed beta-catenin allele, throughout the embryonic mesenchyme. Strikingly, the Dermo...

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Bibliographic Details
Main Authors: Stijn P De Langhe, Gianni Carraro, Denise Tefft, Changgong Li, Xin Xu, Yang Chai, Parviz Minoo, Mohammad K Hajihosseini, Jacques Drouin, Vesa Kaartinen, Savério Bellusci
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2211394?pdf=render

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http://europepmc.org/articles/PMC2211394?pdf=render

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