Decreased circulating C3 levels and mesangial C3 deposition predict renal outcome in patients with IgA nephropathy.

<h4>Background and aims</h4>Mesangial C3 deposition is frequently observed in patients with IgA nephropathy (IgAN). However, the role of complement in the pathogenesis or progression of IgAN is uncertain. In this observational cohort study, we aimed to identify the clinical implications...

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Main Authors: Seung Jun Kim, Hyang Mo Koo, Beom Jin Lim, Hyung Jung Oh, Dong Eun Yoo, Dong Ho Shin, Mi Jung Lee, Fa Mee Doh, Jung Tak Park, Tae-Hyun Yoo, Shin-Wook Kang, Kyu Hun Choi, Hyeon Joo Jeong, Seung Hyeok Han
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22792353/pdf/?tool=EBI