Inferring statistical properties of 3D cell geometry from 2D slices.

Although cell shape can reflect the mechanical and biochemical properties of the cell and its environment, quantification of 3D cell shapes within 3D tissues remains difficult, typically requiring digital reconstruction from a stack of 2D images. We investigate a simple alternative technique to extr...

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Bibliographic Details
Main Authors: Tristan A Sharp, Matthias Merkel, M Lisa Manning, Andrea J Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0209892