Nuclear membrane ruptures, cell death, and tissue damage in the setting of nuclear lamin deficiencies

The nuclear membranes function as a barrier to separate the cell nucleus from the cytoplasm, but this barrier can be compromised by nuclear membrane ruptures, leading to intermixing of nuclear and cytoplasmic contents. Spontaneous nuclear membrane ruptures (i.e., ruptures occurring in the absence of...

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Bibliographic Details
Main Authors: Natalie Y. Chen, Paul H. Kim, Loren G. Fong, Stephen G. Young
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Nucleus
Subjects:
Online Access:http://dx.doi.org/10.1080/19491034.2020.1815410