Molecular characterization of three novel perforins in common carp (Cyprinus carpio L.) and their expression patterns during larvae ontogeny and in response to immune challenges

Molecular characterization of three novel perforins in common carp (Cyprinus carpio L.) and their expression patterns during larvae ontogeny and in response to immune challenges

Abstract Background In the host immune system, perforin is a cytotoxic effector molecule that eliminate virus-infected and malignant cells. Moreover, some recent studies also imply the involvement of perforin in antibacterial immunity. Common carp (Cyprinus carpio L.), one of the most economically i...

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Bibliographic Details
Main Authors: Ting Li, Lei Wang, Yonghuan Zhang, Xinyi Guo, Xinze Chen, Fumiao Zhang, Guiwen Yang, Wujun Wen, Hua Li
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Veterinary Research
Subjects:
Common carp (Cyprinus carpio L.)
Perforin
Evolutionary relationship
Expression pattern
Online Access:http://link.springer.com/article/10.1186/s12917-018-1613-y

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http://link.springer.com/article/10.1186/s12917-018-1613-y

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