Protective effect of CD73 inhibitor α, β-methylene ADP against amyloid-β-induced cognitive impairment by inhibiting adenosine production in hippocampus

Protective effect of CD73 inhibitor α, β-methylene ADP against amyloid-β-induced cognitive impairment by inhibiting adenosine production in hippocampus

Background: Alzheimer's disease (AD) is a chronic, progressive neurodegenerative disease. Recent studies have reported the close association between cognitive function in AD and purinergic receptors in the central nervous system. In the current study, we investigated the effect of CD73 inhibito...

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Bibliographic Details
Main Authors: Wu Song, Yong Tang, Lin Wei, Chi Zhang, Danning Song, Xueting Li, Shuang Jiang
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Electronic Journal of Biotechnology
Subjects:
Acetylcholinesterase
Acetyltransferase
Adenosine
Alzheimer's disease
APCP
ATP
Online Access:http://www.sciencedirect.com/science/article/pii/S0717345820300415

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http://www.sciencedirect.com/science/article/pii/S0717345820300415

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