Pathogenic predictions of non-synonymous variants and their impacts: A computational assessment of ARHGEF6 gene
Introduction: ARHGEF6, a key member and activator of RhoGTPases family that is involved in G-Protein Coupled receptor (GPCR) pathway and stimulate Rho dependent signals in the brain, and mutations in this gene can cause intellectual disability (ID) in Human. Therefore, we aimed to study the conseque...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2018-10-01
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| Series: | Egyptian Journal of Medical Human Genetics |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1110863018300636 |