Expression, Purification and Characterization of the Hepatitis E Virus Like-Particles in the Pichia pastoris

Expression, Purification and Characterization of the Hepatitis E Virus Like-Particles in the Pichia pastoris

Hepatitis E virus (HEV) is associated with acute hepatitis disease, which may lead to chronic disease in immunocompromised individuals. The disease is particularly severe among pregnant women (20–30% mortality). The only licensed vaccine against HEV, which is available in China, is the Escherichia c...

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Bibliographic Details
Main Authors: Jyoti Gupta, Sheetal Kaul, Akriti Srivastava, Neha Kaushik, Sukanya Ghosh, Chandresh Sharma, Gaurav Batra, Manidipa Banerjee, Shalimar, Baibaswata Nayak, C. T. Ranjith-Kumar, Milan Surjit
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Microbiology
Subjects:
viral hepatitis
hepatitis E virus
open reading frame 2
virus-like particle
Pichia pastoris
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00141/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.00141/full

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