Antifibrotic activities of pirfenidone in animal models

Pirfenidone is an orally active small molecule that has recently been evaluated in large clinical trials for the treatment of idiopathic pulmonary fibrosis, a fatal disease in which the uncontrolled deposition of extracellular matrix leads to progressive loss of lung function. This review describes...

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Bibliographic Details
Main Authors: L. Pan, D.W. Ruhrmund, C.J. Schaefer, S.D. Seiwert, K. Kossen
Format: Article
Language:English
Published: European Respiratory Society 2011-06-01
Series:European Respiratory Review
Subjects:
Online Access:http://err.ersjournals.com/content/20/120/85.full.pdf+html