Evolution of mouse circadian enhancers from transposable elements

Abstract Background Transposable elements are increasingly recognized as a source of cis-regulatory variation. Previous studies have revealed that transposons are often bound by transcription factors and some have been co-opted into functional enhancers regulating host gene expression. However, the...

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Bibliographic Details
Main Authors: Julius Judd, Hayley Sanderson, Cédric Feschotte
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-021-02409-9