Utilization of Enzyme-Immobilized Mesoporous Silica Nanocontainers (IBN-4) in Prodrug-Activated Cancer Theranostics

To develop a carrier for use in enzyme prodrug therapy, Horseradish peroxidase (HRP) was immobilized onto mesoporous silica nanoparticles (IBN-4: Institute of Bioengineering and Nanotechnology), where the nanoparticle surfaces were functionalized with 3-aminopropyltrimethoxysilane and further conjug...

Full description

Bibliographic Details
Main Authors: Bau-Yen Hung, Yaswanth Kuthati, Ranjith Kumar Kankala, Shravankumar Kankala, Jin-Pei Deng, Chen-Lun Liu, Chia-Hung Lee
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Nanomaterials
Subjects:
Online Access:http://www.mdpi.com/2079-4991/5/4/2169