Podoplanin drives dedifferentiation and amoeboid invasion of melanoma

Podoplanin drives dedifferentiation and amoeboid invasion of melanoma

Summary: Melanoma is an aggressive skin cancer developing from melanocytes, frequently resulting in metastatic disease. Melanoma cells utilize amoeboid migration as mode of local invasion. Amoeboid invasion is characterized by rounded cell morphology and high actomyosin contractility driven by Rho G...

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Bibliographic Details
Main Authors: Charlotte M. de Winde, Samantha L. George, Eva Crosas-Molist, Yukti Hari-Gupta, Abbey B. Arp, Agnesska C. Benjamin, Lindsey J. Millward, Spyridon Makris, Alexander Carver, Valerio Imperatore, Víctor G. Martínez, Victoria Sanz-Moreno, Sophie E. Acton
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:iScience
Subjects:
Molecular biology
Cell biology
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221009445

Internet

http://www.sciencedirect.com/science/article/pii/S2589004221009445

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