Alterations of the nigrostriatal pathway in a 6-OHDA rat model of Parkinson's disease evaluated with multimodal MRI.

Alterations of the nigrostriatal pathway in a 6-OHDA rat model of Parkinson's disease evaluated with multimodal MRI.

Parkinson's disease is characterized by neurodegeneration of the dopaminergic neurons in the substantia nigra pars compacta. The 6-hydroxydopamine (6-OHDA) rat model has been used to study neurodegeneration in the nigro-striatal dopaminergic system. The goal of this study was to evaluate the re...

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Bibliographic Details
Main Authors: Vincent Perlbarg, Justine Lambert, Benjamin Butler, Mehdi Felfli, Romain Valabrègue, Anne-Laure Privat, Stéphane Lehéricy, Alexandra Petiet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6126820?pdf=render

Internet

http://europepmc.org/articles/PMC6126820?pdf=render

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