Amikacin pharmacokinetic/pharmacodynamic in intensive care unit: a prospective database

Amikacin pharmacokinetic/pharmacodynamic in intensive care unit: a prospective database

Abstract Background Aminoglycosides have a concentration-dependent therapeutic effect when peak serum concentration (C max) reaches eight to tenfold the minimal inhibitory concentration (MIC). With an amikacin MIC of 8 mg/L, the C max should be 64–80 mg/L. This objective is based on clinical breakpo...

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Bibliographic Details
Main Authors: Elsa Logre, Maya Enser, Sébastien Tanaka, Marie Dubert, Aurore Claudinon, Nathalie Grall, Hervé Mentec, Philippe Montravers, Olivier Pajot
Format: Article
Language:English
Published: SpringerOpen 2020-06-01
Series:Annals of Intensive Care
Subjects:
Pharmacokinetic
Pharmacodynamic
Amikacin
Intensive care unit
Online Access:http://link.springer.com/article/10.1186/s13613-020-00685-5

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http://link.springer.com/article/10.1186/s13613-020-00685-5

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