Pursuit of Gene Fusions in Daily Practice: Evidence from Real-World Data in Wild-Type and Microsatellite Instable Patients

Pursuit of Gene Fusions in Daily Practice: Evidence from Real-World Data in Wild-Type and Microsatellite Instable Patients

Agnostic biomarkers such as gene fusions allow to address cancer patients to targeted therapies; however, the low prevalence of these alterations across common malignancies poses challenges and needs a feasible and sensitive diagnostic process. RNA-based targeted next generation sequencing was perfo...

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Bibliographic Details
Main Authors: Enrico Berrino, Alberto Bragoni, Laura Annaratone, Elisabetta Fenocchio, Fabrizio Carnevale-Schianca, Lucia Garetto, Massimo Aglietta, Ivana Sarotto, Laura Casorzo, Tiziana Venesio, Anna Sapino, Caterina Marchiò
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cancers
Subjects:
gene fusions
<i>NTRK</i> genes
next generation sequencing
gene panels
agnostic biomarker
precision medicine
Online Access:https://www.mdpi.com/2072-6694/13/13/3376

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https://www.mdpi.com/2072-6694/13/13/3376

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