The contribution of TWIK-1 channels to astrocyte K+ current is limited by retention in intracellular compartments

The contribution of TWIK-1 channels to astrocyte K+ current is limited by retention in intracellular compartments

TWIK-1 two-pore domain K+ channels are expressed abundantly in astrocytes. In the present study, we examined the extent to which TWIK-1 contributes to the linear current-voltage (I-V) relationship (passive) K+ membrane conductance, a dominant electrophysiological feature of mature hippocampal astroc...

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Bibliographic Details
Main Authors: Wei eWang, Adhytia ePutra, Gary P. Schools, Baofeng eMa, Haijun eChen, Leonard K. Kaczmarek, Jacques eBarhanin, Florian eLesage, Min eZhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Astrocytes
qRT-PCR
patch clamp
western blot
TWIK-1 potassium channel
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00246/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00246/full

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