Haptoglobin Duplicon, Hemoglobin, and Vitamin C: Analyses in the British Women’s Heart and Health Study and Caerphilly Prospective Study

Haptoglobin Duplicon, Hemoglobin, and Vitamin C: Analyses in the British Women’s Heart and Health Study and Caerphilly Prospective Study

Background. Haptoglobin acts as an antioxidant by limiting peroxidative tissue damage by free hemoglobin. The haptoglobin gene allele Hp2 comprises a 1.7 kb partial duplication. Relative to allele Hp1, Hp2 carriers form protein multimers, suboptimal for hemoglobin scavenging. Objective. To examine t...

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Bibliographic Details
Main Authors: Philip A. I. Guthrie, Mohammad R. Abdollahi, Tom Gaunt, Debbie A. Lawlor, Yoav Ben-Shlomo, John Gallacher, George Davey Smith, Ian N. M. Day, Santiago Rodriguez
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2014/529456

Internet

http://dx.doi.org/10.1155/2014/529456

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