Germ-line transmitted, chromosomally integrated HHV-6 and classical Hodgkin lymphoma.

A unique feature of both human herpesvirus 6A and B (HHV-6A and B) among human herpesviruses is their ability to integrate into chromosomal telomeres. In some individuals integrated viral genomes are present in the germ-line and result in the vertical transmission of HHV-6; however, little is known...

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Bibliographic Details
Main Authors: Adam J Bell, Alice Gallagher, Timothy Mottram, Annette Lake, Eleanor V Kane, Tracy Lightfoot, Eve Roman, Ruth F Jarrett
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0112642