Use of a gene score of multiple low-modest effect size variants can predict the risk of obesity better than the individual SNPs
Abstract Background Obesity is a complex disorder, the development of which is modulated by a multitude of environmental, behavioral and genetic factors. The common forms of obesity are polygenic in nature which means that many variants in the same or different genes act synergistically and affect t...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-07-01
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Series: | Lipids in Health and Disease |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12944-018-0806-5 |