O-Linked N-Acetylglucosamine Modification of Mitochondrial Antiviral Signaling Protein Regulates Antiviral Signaling by Modulating Its Activity

O-Linked N-Acetylglucosamine Modification of Mitochondrial Antiviral Signaling Protein Regulates Antiviral Signaling by Modulating Its Activity

Post-translational modifications, including O-GlcNAcylation, play fundamental roles in modulating cellular events, including transcription, signal transduction, and immune signaling. Several molecular targets of O-GlcNAcylation associated with pathogen-induced innate immune responses have been ident...

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Bibliographic Details
Main Authors: Junghwa Seo, Yun Soo Park, Tae Hyun Kweon, Jingu Kang, Seongjin Son, Han Byeol Kim, Yu Ri Seo, Min Jueng Kang, Eugene C. Yi, Yong-ho Lee, Jin-Hong Kim, Boyoun Park, Won Ho Yang, Jin Won Cho
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
host defense mechanism
innate immunity
mitochondrial antiviral signaling protein
O-linked N-Acetylglucosamine (O-GlcNAc)
RIG-I-like receptors signaling
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.589259/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.589259/full

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