Surgical membranes as directional delivery devices to generate tissue: testing in an ovine critical sized defect model.

<h4>Purpose</h4>Pluripotent cells residing in the periosteum, a bi-layered membrane enveloping all bones, exhibit a remarkable regenerative capacity to fill in critical sized defects of the ovine femur within two weeks of treatment. Harnessing the regenerative power of the periosteum app...

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Bibliographic Details
Main Authors: Melissa L Knothe Tate, Hana Chang, Shannon R Moore, Ulf R Knothe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22174873/pdf/?tool=EBI