Melioidosis Patient Survival Correlates With Strong IFN-γ Secreting T Cell Responses Against Hcp1 and TssM

Melioidosis Patient Survival Correlates With Strong IFN-γ Secreting T Cell Responses Against Hcp1 and TssM

Melioidosis, caused by the Gram-negative bacterium Burkholderia pseudomallei, is a serious infectious disease with diverse clinical manifestations. The morbidity and mortality of melioidosis is high in Southeast Asia and no licensed vaccines currently exist. This study was aimed at evaluating human...

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Bibliographic Details
Main Authors: Sineenart Sengyee, Atchara Yarasai, Rachan Janon, Chumpol Morakot, Orawan Ottiwet, Lindsey K. Schmidt, T. Eoin West, Mary N. Burtnick, Narisara Chantratita, Paul J. Brett
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
Burkholderia pseudomallei
melioidosis
T cells
IFN-gamma
Hcp1
TssM
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.698303/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.698303/full

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