Generation of a conditional knockout allele for the NFAT5 gene in mice

The osmosensitive transcription factor nuclear factor of activated T-cells 5 (NFAT5), also known as tonicity enhancer element binding protein (TonEBP) plays a crucial role in protection of renal medullary cells against hyperosmotic stress, urinary concentration, the adaptive immune response, and oth...

Full description

Bibliographic Details
Main Authors: Christoph eKüper, Franz-Xaver eBeck, Wolfgang eNeuhofer
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00507/full