Dynamics of physical interaction between HIV-1 Nef and ASK1: identifying the interacting motif(s).

FasL mediated preferential apoptosis of bystander CTLs while protection of infected CD4(+)T cells remains one of the hallmarks of immune evasion during HIV infection. The property of infected host cells to evade cell-autonomous apoptosis emanates from ability of HIV-1Nef-protein to physically intera...

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Bibliographic Details
Main Authors: Balawant Kumar, Chakrapani Tripathi, Ranjana K Kanchan, Jitendra Kumar Tripathi, Jimut K Ghosh, Ravishankar Ramachandran, Smrati Bhadauria, Raj Kamal Tripathi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3683068?pdf=render