Evolutionary change within a bipotential switch shaped the sperm/oocyte decision in hermaphroditic nematodes.

A subset of transcription factors like Gli2 and Oct1 are bipotential--they can activate or repress the same target, in response to changing signals from upstream genes. Some previous studies implied that the sex-determination protein TRA-1 might also be bipotential; here we confirm this hypothesis b...

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Bibliographic Details
Main Authors: Yiqing Guo, Xiangmei Chen, Ronald E Ellis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3789826?pdf=render