Cytotoxicity of some 1-(2,4-dihydroxyphenyl)-3-(4-phenylpiperidin-1-yl) prop-2-en-1-one derivatives using MTT assay

Cytotoxicity of some 1-(2,4-dihydroxyphenyl)-3-(4-phenylpiperidin-1-yl) prop-2-en-1-one derivatives using MTT assay

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<p>Some N-substituted piperidine structures were synthesized and evaluated for cytotoxic activity against four different cell lines using the standard MTT assay method and Doxorubicin was used as the reference drug. The result of cytotoxic activity as a measurement of IC50 values revealed that...

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Bibliographic Details
Main Authors: Farzaneh Fesahat, Mehdi Khoshneviszadeh, Alireza Foroumadi, Alireza Vahidi, Maryam Fereidounpour, Amirhossein Sakhteman
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2015-02-01
Series:Trends in Pharmaceutical Sciences
Online Access:http://tips.sums.ac.ir/index.php/TiPS/article/view/13

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http://tips.sums.ac.ir/index.php/TiPS/article/view/13

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