A simple, low cost and reusable microfluidic gradient strategy and its application in modeling cancer invasion

Abstract Microfluidic chemical gradient generators enable precise spatiotemporal control of chemotactic signals to study cellular behavior with high resolution and reliability. However, time and cost consuming preparation steps for cell adhesion in microchannels as well as requirement of pumping fac...

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Bibliographic Details
Main Authors: Mohamadmahdi Samandari, Laleh Rafiee, Fatemeh Alipanah, Amir Sanati-Nezhad, Shaghayegh Haghjooy Javanmard
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-89635-0