Development of a dot blot assay with antibodies to recombinant “core” 14-3-3 protein: Evaluation of its usefulness in diagnosis of Creutzfeldt–Jakob disease

Development of a dot blot assay with antibodies to recombinant “core” 14-3-3 protein: Evaluation of its usefulness in diagnosis of Creutzfeldt–Jakob disease

Background and Purpose: Definitive diagnosis of Creutzfeldt–Jakob disease (CJD) requires demonstration of infective prion protein (PrPSc) in brain tissues by immunohistochemistry or immunoblot, making antemortem diagnosis of CJD difficult. The World Health Organization (WHO) recommends detection of...

Full description

Bibliographic Details
Main Authors: Sarada Subramanian, Anita Mahadevan, Parthasarathy Satishchandra, Susarla Krishna Shankar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Annals of Indian Academy of Neurology
Subjects:
Core 14-3-3 protein
Creutzfeldt–Jakob disease (CJD)
dot blot
overlapping polymerase chain reaction (PCR)
synthetic gene
Online Access:http://www.annalsofian.org/article.asp?issn=0972-2327;year=2016;volume=19;issue=2;spage=205;epage=210;aulast=Subramanian

Internet

http://www.annalsofian.org/article.asp?issn=0972-2327;year=2016;volume=19;issue=2;spage=205;epage=210;aulast=Subramanian

Similar Items